Structures of human telomerase with BIBR1532 reveal novel mechanism of inhibition

Keyword: Human Immunodeficiency Virus (hiv)

Publisher: Nature.com

Published: Jun 2, 2026

Identification of the BIBR1532-binding pocket on telomerase For cryo-EM studies, human telomerase in complex with DNA primer d(TTAGGG)3 and the shelterin protein TPP1 OB domain (hereafter referred t… [+28858 chars]

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