Curcumin derivatives with 1,5-diaryl-3-oxo-1,4-pentadiene: novel dual-function lead compounds showing anticancer and MDR reversal effects

Keyword: Drug Resistance

Publisher: Royal Society of Chemistry

Published: May 19, 2026

1,5-Diaryl-3-oxo-1,4-pentadiene is an excellent pharmacophore derived from Curcumin. Synthesis of six focused 1,5-diaryl-3-oxo-1,4-pentadiene libraries (1a1e, 2a2e, 3a3e, 4a4e, 5a5e and intermediates… [+1316 chars]

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