MAPLE enables ultrasensitive detection of low-frequency cfDNA methylation haplotypes using short capture probes with cost-efficient performance

Keyword: Blood Plasma

Publisher: Cshlp.org

Published: Jun 15, 2026

One major challenge in disease detection using methylation biomarkers is accurately identifying low-frequency, disease-specific methylation haplotypes. Conventional methods detect these haplotypes us… [+1680 chars]

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