Indoxyl sulfate–associated vascular calcification is linked to mTORC1 and ER stress–integrated stress response signaling

Keyword: Senescence

Publisher: Nature.com

Published: Sep 3, 2026

Medial vascular calcification is a major cardiovascular complication of chronic kidney disease (CKD), with the uremic toxin indoxyl sulfate (IS) implicated in its pathogenesis. However, the molecular… [+1030 chars]

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