Research Radar

Academic Publication • Published Jul 9, 2024

Towards the automation of systematic reviews using natural language processing, machine learning, and deep learning: a comprehensive review

AbstractSystematic reviews (SRs) constitute a critical foundation for evidence-based decision-making and policy formulation across various disciplines, particularly in healthcare and beyond. However, the inherently rigorous and structured nature o...

Academic Publication • Published Jul 9, 2024

All-in-One Alkaline Phosphatase-Response Aggregation-Induced Emission Probe for Cancer Discriminative Imaging and Combinational Chemodynamic–Photodynamic Therapy

Academic Publication • Published Jul 9, 2024

Multifaceted Carbonized Metal–Organic Frameworks Synergize with Immune Checkpoint Inhibitors for Precision and Augmented Cuproptosis Cancer Therapy

Academic Publication • Published Jul 9, 2024

Colloquium : Quantum batteries

Academic Publication • Published Jul 9, 2024

Comparing Conventional and Advanced Approaches for Heavy Metal Removal in Wastewater Treatment: An In-Depth Review Emphasizing Filter-Based Strategies

Various industrial activities release heavy metal ions into the environment, which represent one of the major toxic pollutants owing to their severe effects on the environment, humans, and all living species. Despite several technological advances...

Academic Publication • Published Jul 8, 2024

The ethics of ChatGPT in medicine and healthcare: a systematic review on Large Language Models (LLMs)

AbstractWith the introduction of ChatGPT, Large Language Models (LLMs) have received enormous attention in healthcare. Despite potential benefits, researchers have underscored various ethical implications. While individual instances have garnered ...

Academic Publication • Published Jul 8, 2024

Transformative Technologies in Digital Agriculture: Leveraging Internet of Things, Remote Sensing, and Artificial Intelligence for Smart Crop Management

This paper explores the potential of smart crop management based on the incorporation of tools like digital agriculture, which considers current technological tools applied in agriculture, such as the Internet of Things (IoT), remote sensing, and ...

Academic Publication • Published Jul 7, 2024

Emerging Therapeutic Strategies to Overcome Drug Resistance in Cancer Cells

The rise of drug resistance in cancer cells presents a formidable challenge in modern oncology, necessitating the exploration of innovative therapeutic strategies. This review investigates the latest advancements in overcoming drug resistance mech...

Academic Publication • Published Jul 5, 2024

Advanced Plasmonic Resonance-enhanced Biosensor for Comprehensive Real-time Detection and Analysis of Deepfake Content

Academic Publication • Published Jul 5, 2024

MicroRNAs: circulating biomarkers for the early detection of imperceptible cancers via biosensor and machine-learning advances

AbstractThis review explores the topic of microRNAs (miRNAs) for improved early detection of imperceptible cancers, with potential to advance precision medicine and improve patient outcomes. Historical research exploring miRNA’s role in cancer det...

Academic Publication • Published Jul 5, 2024

Exploring and retrieving sequence and metadata for species across the tree of life with NCBI Datasets

AbstractTo explore complex biological questions, it is often necessary to access various data types from public data repositories. As the volume and complexity of biological sequence data grow, public repositories face significant challenges in en...

Academic Publication • Published Jul 5, 2024

ADMETlab 3.0: an updated comprehensive online ADMET prediction platform enhanced with broader coverage, improved performance, API functionality and decision support

Abstract ADMETlab 3.0 is the second updated version of the web server that provides a comprehensive and efficient platform for evaluating ADMET-related parameters as well as physicochemical properties and medicinal chemistry charact...

Academic Publication • Published Jul 5, 2024

DeepLoc 2.1: multi-label membrane protein type prediction using protein language models

Abstract DeepLoc 2.0 is a popular web server for the prediction of protein subcellular localization and sorting signals. Here, we introduce DeepLoc 2.1, which additionally classifies the input proteins into the membrane protein type...

Academic Publication • Published Jul 5, 2024

The EMBL-EBI Job Dispatcher sequence analysis tools framework in 2024

Abstract The EMBL-EBI Job Dispatcher sequence analysis tools framework (https://www.ebi.ac.uk/jdispatcher) enables the scientific community to perform a diverse range of sequence analyses using popular bioinformatics applications. F...

Academic Publication • Published Jul 5, 2024

MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation

Abstract We introduce MetaboAnalyst version 6.0 as a unified platform for processing, analyzing, and interpreting data from targeted as well as untargeted metabolomics studies using liquid chromatography - mass spectrometry (LC–MS)....

Academic Publication • Published Jul 5, 2024

Deep-PK: deep learning for small molecule pharmacokinetic and toxicity prediction

Abstract Evaluating pharmacokinetic properties of small molecules is considered a key feature in most drug development and high-throughput screening processes. Generally, pharmacokinetics, which represent the fate of drugs in the hu...

Academic Publication • Published Jul 5, 2024

Interactive Tree of Life (iTOL) v6: recent updates to the phylogenetic tree display and annotation tool

Abstract The Interactive Tree Of Life (https://itol.embl.de) is an online tool for the management, display, annotation and manipulation of phylogenetic and other trees. It is freely available and open to everyone. iTOL version 6 int...

Academic Publication • Published Jul 5, 2024

The structure assessment web server: for proteins, complexes and more

Abstract The ‘structure assessment’ web server is a one-stop shop for interactive evaluation and benchmarking of structural models of macromolecular complexes including proteins and nucleic acids. A user-friendly web dashboard links...

Academic Publication • Published Jul 5, 2024

admetSAR3.0: a comprehensive platform for exploration, prediction and optimization of chemical ADMET properties

Abstract Absorption, distribution, metabolism, excretion and toxicity (ADMET) properties play a crucial role in drug discovery and chemical safety assessment. Built on the achievements of admetSAR and its successor, admetSAR2.0, thi...

Academic Publication • Published Jul 5, 2024

ProTox 3.0: a webserver for the prediction of toxicity of chemicals

Abstract Interaction with chemicals, present in drugs, food, environments, and consumer goods, is an integral part of our everyday life. However, depending on the amount and duration, such interactions can also result in adverse eff...