Research Radar

Academic Publication • Published Jun 11, 2024

Global nitrous oxide budget (1980–2020)

Abstract. Nitrous oxide (N2O) is a long-lived potent greenhouse gas and stratospheric ozone-depleting substance that has been accumulating in the atmosphere since the preindustrial period. The mole fraction of atmospheric N2O has increased by near...

Academic Publication • Published Jun 10, 2024

PACE: A Randomized Phase II Study of Fulvestrant, Palbociclib, and Avelumab After Progression on Cyclin-Dependent Kinase 4/6 Inhibitor and Aromatase Inhibitor for Hormone Receptor–Positive/Human Epidermal Growth Factor Receptor–Negative Metastatic Breast Cancer

PURPOSE Cyclin-dependent kinase (CDK) 4/6 inhibitors (CDK4/6is) are an important component of treatment for hormone receptor–positive/human epidermal growth factor receptor 2–negative (HER2–) metastatic breast cancer (MBC), but it is not known if ...

Academic Publication • Published Jun 10, 2024

Artificial Intelligence in Smart Cities—Applications, Barriers, and Future Directions: A Review

As urbanization continues to pose new challenges for cities around the world, the concept of smart cities is a promising solution, with artificial intelligence (AI) playing a central role in this transformation. This paper presents a literature re...

Academic Publication • Published Jun 10, 2024

Cooling Benefits of Urban Tree Canopy: A Systematic Review

As an important part of urban ecosystems, trees can effectively alleviate the urban heat island effect. Tree canopies cool and humidify through shading and evapotranspiration, regulating the urban thermal environment. So far, many studies have ana...

Academic Publication • Published Jun 8, 2024

Random Forest Algorithm Overview

A random forest is a machine learning model utilized in classification and forecasting. To train machine learning algorithms and artificial intelligence models, it is crucial to have a substantial amount of high-quality data for effective data col...

Academic Publication • Published Jun 7, 2024

Global, regional, and national burden and trends of migraine among women of childbearing age from 1990 to 2021: insights from the Global Burden of Disease Study 2021

Abstract Background Migraine, a neurological disorder with a significant female predilection, is the leading cause of disability-adjusted life years (DALYs) in women of childbearing age (WCBA). There is currently a ...

Academic Publication • Published Jun 6, 2024

A whole-slide foundation model for digital pathology from real-world data

AbstractDigital pathology poses unique computational challenges, as a standard gigapixel slide may comprise tens of thousands of image tiles1–3. Prior models have often resorted to subsampling a small portion of tiles for each slide, thus missing ...

Academic Publication • Published Jun 6, 2024

Genome Sequencing for Diagnosing Rare Diseases

Academic Publication • Published Jun 5, 2024

Facet-Dependent Surface Restructuring on Nickel (Oxy)hydroxides: A Self-Activation Process for Enhanced Oxygen Evolution Reaction

Academic Publication • Published Jun 5, 2024

High internal phase emulsions gel ink for direct-ink-writing 3D printing of liquid metal

Abstract3D printing of liquid metal remains a big challenge due to its low viscosity and large surface tension. In this study, we use Carbopol hydrogel and liquid gallium-indium alloy to prepare a liquid metal high internal phase emulsion gel ink,...

Academic Publication • Published Jun 5, 2024

Indicators of Global Climate Change 2023: annual update of key indicators of the state of the climate system and human influence

Abstract. Intergovernmental Panel on Climate Change (IPCC) assessments are the trusted source of scientific evidence for climate negotiations taking place under the United Nations Framework Convention on Climate Change (UNFCCC). Evidence-based dec...

Academic Publication • Published Jun 4, 2024

Bright Innovations: Review of Next-Generation Advances in Scintillator Engineering

Academic Publication • Published Jun 4, 2024

Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study

Abstract In contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced th...

Academic Publication • Published Jun 4, 2024

2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

AIM: The “2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy” provides recommendations to guide clinicians in the management of patients with hypertrophic cardiomyopathy. ...

Academic Publication • Published Jun 4, 2024

Sodium-Glucose Cotransporter-2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis

BACKGROUND: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) consistently improve heart failure and kidney-related outcomes; however, effects on major adverse cardiovascular events (MACE) across different patient populations are less...

Academic Publication • Published Jun 3, 2024

KRAGEN: a knowledge graph-enhanced RAG framework for biomedical problem solving using large language models

Abstract Motivation Answering and solving complex problems using a large language model (LLM) given a certain domain such as biomedicine is a challenging task that requires both factual consisten...

Academic Publication • Published Jun 3, 2024

RCSB protein Data Bank: exploring protein 3D similarities via comprehensive structural alignments

Abstract Motivation Tools for pairwise alignments between 3D structures of proteins are of fundamental importance for structural biology and bioinformatics, enabling visual exploration of evoluti...

Academic Publication • Published Jun 3, 2024

Power Hungry Processing: Watts Driving the Cost of AI Deployment?

Academic Publication • Published Jun 3, 2024

"I'm Not Sure, But...": Examining the Impact of Large Language Models' Uncertainty Expression on User Reliance and Trust

Academic Publication • Published Jun 3, 2024

Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer

Abstract Understanding the role of the tumor microenvironment (TME) in lung cancer is critical to improving patient outcomes. We identified four histology-independent archetype TMEs in tr...