Academic Publication Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway
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Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway
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Emerging insights into the pathogenesis and therapeutic strategies for vascular endothelial injury-associated diseases: focus on mitochondrial dysfunction
AbstractAs a vital component of blood vessels, endothelial cells play a key role in maintaining overall physiological function by residing between circulating blood and semi-solid tissue. Various s...
Mitochondrial dysfunction: mechanisms and advances in therapy
AbstractMitochondria, with their intricate networks of functions and information processing, are pivotal in both health regulation and disease progression. Particularly, mitochondrial dysfunctions ...
Triose phosphate isomerase 1 remodels mitochondrial cristae ultrastructure to rewire microglial immunometabolism against ischemic stroke
Mitochondrial cristae structure is essential for energy production and immune regulation, but therapeutic strategies targeting cristae remodeling are lacking. Here, the authors show that targeting ...
A fatty acid amide activates myeloid cells and improves neurovascular outcomes in retinal degeneration
Erucamide, a fatty acid amide reduced in degenerating retinas, activates myeloid cells via TMEM19 to release neurotrophic and angiogenic factors, rescuing photoreceptors and vasculature in mouse mo...
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Yes, highly correlated activity was mapped. An entry titled 'Triose phosphate isomerase 1 remodels mitochondrial cristae ultrastructure to rewire microglial immunometabolism against ischemic stroke' discusses this: Mitochondrial cristae structure is essential for energy production and immune regulation, but therapeutic strategies targeting cristae remodeling a...
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Associated Media Narrative
- Acute ischemic stroke and intracerebral hemorrhage are two distinct diseases in immunology
- Microglial mitochondria transfer to astrocytes via GPNMB-enriched extracellular vesicles alleviates cognitive deficits in tauopathy mice
- Multiscale modeling of blood circulation with cerebral autoregulation and network pathway analysis for hemodynamic redistribution in the vascular network with anatomical variations and stenosis conditions
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