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Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway

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November 1, 2024
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crossref.org › academic paper
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Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway

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crossref.org › academic paper
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Triose phosphate isomerase 1 remodels mitochondrial cristae ultrastructure to rewire microglial immunometabolism against ischemic stroke

Mitochondrial cristae structure is essential for energy production and immune regulation, but therapeutic strategies targeting cristae remodeling are lacking. Here, the authors show that targeting ...

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A fatty acid amide activates myeloid cells and improves neurovascular outcomes in retinal degeneration

Erucamide, a fatty acid amide reduced in degenerating retinas, activates myeloid cells via TMEM19 to release neurotrophic and angiogenic factors, rescuing photoreceptors and vasculature in mouse mo...

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Yes, highly correlated activity was mapped. An entry titled 'Triose phosphate isomerase 1 remodels mitochondrial cristae ultrastructure to rewire microglial immunometabolism against ischemic stroke' discusses this: Mitochondrial cristae structure is essential for energy production and immune regulation, but therapeutic strategies targeting cristae remodeling a...

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