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Academic Publication Tandem-controlled lysosomal assembly of nanofibres induces pyroptosis for cancer immunotherapy
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Tandem-controlled lysosomal assembly of nanofibres induces pyroptosis for cancer immunotherapy
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Glutathione‐Scavenging Celastrol‐Cu Nanoparticles Induce Self‐Amplified Cuproptosis for Augmented Cancer Immunotherapy
AbstractCuproptosis is a novel copper‐dependent programmed cell death. The efficacy of cuproptosis is highly dependent on intracellular copper accumulation and counteracted by a high level of gluta...
Targeting the Labile Iron Pool with Engineered DFO Nanosheets to Inhibit Ferroptosis for Parkinson's Disease Therapy
AbstractFerroptosis in neurons is considered one of the key factors that induces Parkinson's disease (PD), which is caused by excessive iron accumulation in the intracellular labile iron pool (LIP)...
Self-Cascaded Pyroptosis-STING Initiators for Catalytic Metalloimmunotherapy
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In vivo CAR T cell generation to treat cancer and autoimmune disease
Chimeric antigen receptor (CAR) T cell therapies have transformed treatment of B cell malignancies. However, their broader application is limited by complex manufacturing processes and the necessit...
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