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Abstract
In the context of global ageing, the prevalence of neurodegenerative diseases and dementia, such as Alzheimer’s disease (AD), is increasing. However, the current symptomatic and disease-modifying therapies have achieved limited benefits for neurodegenerative diseases in clinical settings. Halting the progress of neurodegeneration and cognitive decline or even improving impaired cognition and function are the clinically meaningful goals of treatments for neurodegenerative diseases. Ageing is the primary risk factor for neurodegenerative diseases and their associated comorbidities, such as vascular pathologies, in elderly individuals. Thus, we aim to elucidate the role of ageing in neurodegenerative diseases from the perspective of a complex system, in which the brain is the core and peripheral organs and tissues form a holistic network to support brain functions. During ageing, the progressive deterioration of the structure and function of the entire body hampers its active and adaptive responses to various stimuli, thereby rendering individuals more vulnerable to neurodegenerative diseases. Consequently, we propose that the prevention and treatment of neurodegenerative diseases should be grounded in holistic antiageing and rejuvenation means complemented by interventions targeting disease-specific pathogenic events. This integrated approach is a promising strategy to effectively prevent, pause or slow down the progression of neurodegenerative diseases.
Academic Publication Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances
Research Abstract & Technology Focus
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Alzheimer’s disease unveiled: Cutting-edge multi-modal neuroimaging and computational methods for enhanced diagnosis
No description provided.
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What is the core focus of the research titled 'Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances'?
This literature focuses on: Abstract In the context of global ageing, the prevalence of neurodegenerative diseases and dementia, such as Alzheimer’s disease (AD), is increasing. However, the current symptomatic and disease-modifying therapies have achieved limited ...
Are there open-source GitHub repositories related to Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances?
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Which startups are commercializing the technology behind Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances?
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What other academic literature is closely related to 'Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances'?
Yes, highly correlated activity was mapped. An entry titled 'Alzheimer’s disease unveiled: Cutting-edge multi-modal neuroimaging and computational methods for enhanced diagnosis' discusses this: No description provided.
Are there commercial applications of 'Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances' in market news publications?
Yes, highly correlated activity was mapped. An entry titled 'Scientists say NAD+ could slow aging and fight Alzheimer’s and Parkinson’s' discusses this: A global team of leading scientists is zeroing in on a tiny but powerful molecule that could reshape how we age. Known as NAD⁺, it plays a crucial ...
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GitHubphuryn/pm-skills
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Product HuntBlaze 2.0