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Pathogenesis Research & Models

Pathogenesis

Origin Data Source OpenAlex
Analysis Computed Jul 30, 2026
AI Synthesis & Market Narrative
Advanced research is elucidating disease pathogenesis across multiple domains, from nanozyme development targeting atherosclerosis mechanisms to CRISPR-Cas systems in bacterial immunity. New animal models are being developed to investigate viral pathogenesis, indicating a focus on foundational understanding for therapeutic development.
Correlated Linguistic Patterns
["multi-pathway treatment of atherosclerosis through anti-oxidation and pro-efferocytosis" "CRISPR\u2013Cas regulates expression of embedded anti-phage defence systems" "IL-10\/JAK\u2013STAT signaling in the proliferative changes of retinopathy of prematurity" "new models for investigating mpox infection and pathogenesis"]
Driving Media Context
Nature.com • Jul 23, 2026

Bioinspired porous metal-amino acid nanozymes enable multi-pathway treatment of atherosclerosis through anti-oxidation and pro-efferocytosis

Atherosclerosis is driven by chronic inflammation and persistent oxidative stress accompanied by cholesterol deposition in the intimal layer and impaired eff...
Nature.com • Jul 22, 2026

CRISPR–Cas regulates expression of embedded anti-phage defence systems

CRISPR–Cas systems transcriptionally tune diverse innate defences using CRISPR RNA-like guides to balance antiviral protection with fitness, and hyperactivat...
Inside Higher Ed • Jul 21, 2026

Treat Your Students Like Scientists

Treat Your Students Like Scientists Elizabeth Redden Tue, 07/21/2026 - 03:00 AM Fixing the leaky pipeline depends on it. Byline(s) Kristi Ru...
Nature.com • Jul 15, 2026

High-sensitivity vitreous proteomic analyses reveal involvement of IL-10/JAK–STAT signaling in the proliferative changes of retinopathy of prematurity

Scientific Reports - High-sensitivity vitreous proteomic analyses reveal involvement of IL-10/JAK–STAT signaling in the proliferative changes of retinopathy ...
GlobeNewswire • Jul 15, 2026

Tonix Pharmaceuticals Announces Publication in the Peer-Reviewed Journal of Virology Assessing Virulence of the 2022 Outbreak Strain of Mpox in New Animal Models

Data show clade IIb from 2022 outbreak is 100 to 100,000-fold less virulent than clade IIa from 2003 outbreak Three new models for investigating mpox...
Nature.com • Jul 13, 2026

Nuclear condensates formed by truncated mutant NEK1s impede ribosomal RNA biogenesis and drive motor dysfunction

This study shows that ALS-related NEK1 nonsense mutants form nuclear biomolecular condensates, interfere with ribosomal RNA biogenesis, and reveal a gain-of-...
Science Daily • Jul 11, 2026

Experimental drug reverses severe fatty liver disease by repairing the gut

An experimental drug called DT-109 reversed severe fatty liver disease in animal studies by repairing the gut and preventing harmful toxins from damaging the...
PRNewswire • Jul 9, 2026

Professor Gang Shen's Orthodontic Team Publishes Third Consecutive Paper in the Journal of Aligner Orthodontics

SHANGHAI, July 8, 2026 /PRNewswire/ -- Professor Gang Shen, Chief GS R&D Scientist of Smartee Denti-Technology and Chief Orthodontist at Taikang Dental, toge...
Nature.com • Jul 8, 2026

Chromatin landscape and epigenetic heterogeneity of acute myeloid leukaemia

An ATAC-seq-based approach is used to classify acute myeloid leukaemia (AML) into 16 epigenomic subgroups, and provides insight into the role of non-genetic ...
Plos.org • Jul 8, 2026

Multi-regional transcriptomic profiling reveals divergent molecular mechanisms in ALS-related neurodegeneration

Author summary Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons. While mutatio...