Pathogenesis Research & Models
Pathogenesis
AI Synthesis & Market Narrative
Advanced research is elucidating disease pathogenesis across multiple domains, from nanozyme development targeting atherosclerosis mechanisms to CRISPR-Cas systems in bacterial immunity. New animal models are being developed to investigate viral pathogenesis, indicating a focus on foundational understanding for therapeutic development.
Correlated Linguistic Patterns
["multi-pathway treatment of atherosclerosis through anti-oxidation and pro-efferocytosis"
"CRISPR\u2013Cas regulates expression of embedded anti-phage defence systems"
"IL-10\/JAK\u2013STAT signaling in the proliferative changes of retinopathy of prematurity"
"new models for investigating mpox infection and pathogenesis"]
Driving Media Context
Bioinspired porous metal-amino acid nanozymes enable multi-pathway treatment of atherosclerosis through anti-oxidation and pro-efferocytosis
Atherosclerosis is driven by chronic inflammation and persistent oxidative stress accompanied by cholesterol deposition in the intimal layer and impaired eff...
CRISPR–Cas regulates expression of embedded anti-phage defence systems
CRISPR–Cas systems transcriptionally tune diverse innate defences using CRISPR RNA-like guides to balance antiviral protection with fitness, and hyperactivat...
Treat Your Students Like Scientists
Treat Your Students Like Scientists
Elizabeth Redden
Tue, 07/21/2026 - 03:00 AM
Fixing the leaky pipeline depends on it.
Byline(s)
Kristi Ru...
High-sensitivity vitreous proteomic analyses reveal involvement of IL-10/JAK–STAT signaling in the proliferative changes of retinopathy of prematurity
Scientific Reports - High-sensitivity vitreous proteomic analyses reveal involvement of IL-10/JAK–STAT signaling in the proliferative changes of retinopathy ...
Tonix Pharmaceuticals Announces Publication in the Peer-Reviewed Journal of Virology Assessing Virulence of the 2022 Outbreak Strain of Mpox in New Animal Models
Data show clade IIb from 2022 outbreak is 100 to 100,000-fold less virulent than clade IIa from 2003 outbreak Three new models for investigating mpox...
Nuclear condensates formed by truncated mutant NEK1s impede ribosomal RNA biogenesis and drive motor dysfunction
This study shows that ALS-related NEK1 nonsense mutants form nuclear biomolecular condensates, interfere with ribosomal RNA biogenesis, and reveal a gain-of-...
Experimental drug reverses severe fatty liver disease by repairing the gut
An experimental drug called DT-109 reversed severe fatty liver disease in animal studies by repairing the gut and preventing harmful toxins from damaging the...
Professor Gang Shen's Orthodontic Team Publishes Third Consecutive Paper in the Journal of Aligner Orthodontics
SHANGHAI, July 8, 2026 /PRNewswire/ -- Professor Gang Shen, Chief GS R&D Scientist of Smartee Denti-Technology and Chief Orthodontist at Taikang Dental, toge...
Chromatin landscape and epigenetic heterogeneity of acute myeloid leukaemia
An ATAC-seq-based approach is used to classify acute myeloid leukaemia (AML) into 16 epigenomic subgroups, and provides insight into the role of non-genetic ...
Multi-regional transcriptomic profiling reveals divergent molecular mechanisms in ALS-related neurodegeneration
Author summary Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons. While mutatio...
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