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KRAGEN: a knowledge graph-enhanced RAG framework for biomedical problem solving using large language models

92
Citations
June 3, 2024
Published Date

Research Abstract & Technology Focus

Abstract

Motivation
Answering and solving complex problems using a large language model (LLM) given a certain domain such as biomedicine is a challenging task that requires both factual consistency and logic, and LLMs often suffer from some major limitations, such as hallucinating false or irrelevant information, or being influenced by noisy data. These issues can compromise the trustworthiness, accuracy, and compliance of LLM-generated text and insights.


Results
Knowledge Retrieval Augmented Generation ENgine (KRAGEN) is a new tool that combines knowledge graphs, Retrieval Augmented Generation (RAG), and advanced prompting techniques to solve complex problems with natural language. KRAGEN converts knowledge graphs into a vector database and uses RAG to retrieve relevant facts from it. KRAGEN uses advanced prompting techniques: namely graph-of-thoughts (GoT), to dynamically break down a complex problem into smaller subproblems, and proceeds to solve each subproblem by using the relevant knowledge through the RAG framework, which limits the hallucinations, and finally, consolidates the subproblems and provides a solution. KRAGEN’s graph visualization allows the user to interact with and evaluate the quality of the solution’s GoT structure and logic.


Availability and implementation
KRAGEN is deployed by running its custom Docker containers. KRAGEN is available as open-source from GitHub at: https://github.com/EpistasisLab/KRAGEN.
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What is the core focus of the research titled 'KRAGEN: a knowledge graph-enhanced RAG framework for biomedical problem solving using large language models'?

This literature focuses on: Abstract Motivation Answering and solving complex problems using a large language model (LLM) given a certain domain such as biomedicine is a challenging task that requires both factual consisten...

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Products like WUPHF by Nex.ai are bringing this to market. Their focus is: AI employees who build their own knowledge base.

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Yes, highly correlated activity was mapped. An entry titled 'KRAGEN: a knowledge graph-enhanced RAG framework for biomedical problem solving using large language models' discusses this: Abstract Motivation Answering and solving complex problems using a large language model (LLM) g...

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