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Abstract
With their diverse biological activities, peptides are promising candidates for therapeutic applications, showing antimicrobial, antitumour and hormonal signalling capabilities. Despite their advantages, therapeutic peptides face challenges such as short half-life, limited oral bioavailability and susceptibility to plasma degradation. The rise of computational tools and artificial intelligence (AI) in peptide research has spurred the development of advanced methodologies and databases that are pivotal in the exploration of these complex macromolecules. This perspective delves into integrating AI in peptide development, encompassing classifier methods, predictive systems and the avant-garde design facilitated by deep-generative models like generative adversarial networks and variational autoencoders. There are still challenges, such as the need for processing optimization and careful validation of predictive models. This work outlines traditional strategies for machine learning model construction and training techniques and proposes a comprehensive AI-assisted peptide design and validation pipeline. The evolving landscape of peptide design using AI is emphasized, showcasing the practicality of these methods in expediting the development and discovery of novel peptides within the context of peptide-based drug discovery.
Academic Publication Peptide-based drug discovery through artificial intelligence: towards an autonomous design of therapeutic peptides
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Peptide-based drug discovery through artificial intelligence: towards an autonomous design of therapeutic peptides
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What is the core focus of the research titled 'Peptide-based drug discovery through artificial intelligence: towards an autonomous design of therapeutic peptides'?
This literature focuses on: Abstract With their diverse biological activities, peptides are promising candidates for therapeutic applications, showing antimicrobial, antitumour and hormonal signalling capabilities. Despite their advantages, therapeutic peptide...
Are there open-source GitHub repositories related to Peptide-based drug discovery through artificial intelligence: towards an autonomous design of therapeutic peptides?
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What other academic literature is closely related to 'Peptide-based drug discovery through artificial intelligence: towards an autonomous design of therapeutic peptides'?
Yes, highly correlated activity was mapped. An entry titled 'Peptide-based drug discovery through artificial intelligence: towards an autonomous design of therapeutic peptides' discusses this: Abstract With their diverse biological activities, peptides are promising candidates for therapeutic applications, showing antimicro...
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GitHubphuryn/pm-skills
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GitHubgoogleworkspace/cli
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Product HuntDeconflict
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Product HuntNomNak