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Abstract
The aim of the UniProt Knowledgebase (UniProtKB; https://www.uniprot.org/) is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information. In this publication, we describe ongoing changes to our production pipeline to limit the sequences available in UniProtKB to high-quality, non-redundant reference proteomes. We continue to manually curate the scientific literature to add the latest functional data and use machine learning techniques. We also encourage community curation to ensure key publications are not missed. We provide an update on the automatic annotation methods used by UniProtKB to predict information for unreviewed entries describing unstudied proteins. Finally, updates to the UniProt website are described, including a new tab linking protein to genomic information. In recognition of its value to the scientific community, the UniProt database has been awarded Global Core Biodata Resource status.
Academic Publication UniProt: the Universal Protein Knowledgebase in 2025
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UniProt: the Universal Protein Knowledgebase in 2025
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Frequently Asked Questions (FAQ)
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What is the core focus of the research titled 'UniProt: the Universal Protein Knowledgebase in 2025'?
This literature focuses on: Abstract The aim of the UniProt Knowledgebase (UniProtKB; https://www.uniprot.org/) is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information. In this...
Are there open-source GitHub repositories related to UniProt: the Universal Protein Knowledgebase in 2025?
Yes, open-source projects like jackwener/opencli (Make Any Website & Tool Your CLI. A universal CLI Hub and AI-native runtime. Transform any website, Electron app, or local binary into a standardiz...) are actively building upon these concepts.
Which startups are commercializing the technology behind UniProt: the Universal Protein Knowledgebase in 2025?
Products like FileFlan are bringing this to market. Their focus is: Instant private universal file sharing.
What other academic literature is closely related to 'UniProt: the Universal Protein Knowledgebase in 2025'?
Yes, highly correlated activity was mapped. An entry titled 'UniProt: the Universal Protein Knowledgebase in 2025' discusses this: Abstract The aim of the UniProt Knowledgebase (UniProtKB; https://www.uniprot.org/) is to provide users with a comprehensive, high-q...
Are there commercial applications of 'UniProt: the Universal Protein Knowledgebase in 2025' in market news publications?
Yes, highly correlated activity was mapped. An entry titled 'AlphaFold hits ‘next level’: the AI tool now includes protein pairing' discusses this: The database of 200 million protein-structure predictions now includes homodimers, adding new biological relevance.
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Commercial Realization
Startups and Open Source tools heavily associated with the concepts explored in this paper.
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GitHubjackwener/opencli
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GitHubHelvesec/rmux
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Product HuntFileFlan