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Academic Publication Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling
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Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling
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Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism
A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells.
Xyloglucan xylosyltransferase stem region mediates heterodimer formation
The crystal structure of xyloglucan xylosyltransferases XXT2 and XXT5 reveals an obligate heterodimer, in which XXT2’s flexible stem binds the catalytic domain of XXT5. Heterodimer assembly is also...
Conformational landscape and ligand-dependent clustering of the human type 2 IP3 receptor
Here the authors define the conformational landscape of human IP3R-2 and identify a ligand-dependent inter-channel interface that mediates receptor clustering during calcium signalling.
MechanochemicallyCoupled Multidimensional Modulationof Calcium Overload
Disruption of calcium ion (Ca2+) homeostasis has emerged as a promising strategy for tumor therapy. However, the intricate regulation of Ca2+ signaling and the limitations of single-dimensional mod...
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What other academic literature is closely related to 'Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling'?
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Yes, highly correlated activity was mapped. An entry titled 'Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism' discusses this: A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendri...
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