Academic Publication Epigenetic ageing clocks: statistical methods and emerging computational challenges
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Nonlinear dynamics of multi-omics profiles during human aging
AbstractAging is a complex process associated with nearly all diseases. Understanding the molecular changes underlying aging and identifying therapeutic targets for aging-related diseases are cruci...
Analysis of cell-free DNA for cancer diagnostics using liquid biopsies
Chromatin organisation influences gene regulation and genome stability, yet its dysregulation in cancer remains incompletely understood. This has become particularly important for patient diagnosti...
AlphaGenome: advancing regulatory variant effect prediction with a unified DNA sequence model
Deep learning models that predict functional genomic measurements from DNA sequence are powerful tools for deciphering the genetic regulatory code. Existing methods trade off between input sequence...
ChIP-Atlas 3.0: a data-mining suite to explore chromosome architecture together with large-scale regulome data
Abstract ChIP-Atlas (https://chip-atlas.org/) presents a suite of data-mining tools for analyzing epigenomic landscapes, powered by the comprehensive integration of over 376 000 publ...
A technical review of multi-omics data integration methods: from classical statistical to deep generative approaches
Abstract The rapid advancement of high-throughput sequencing and other assay technologies has resulted in the generation of large and complex multi-omics datasets, offering unprecede...
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Yes, highly correlated activity was mapped. An entry titled 'Nonlinear dynamics of multi-omics profiles during human aging' discusses this: AbstractAging is a complex process associated with nearly all diseases. Understanding the molecular changes underlying aging and identifying therap...
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Associated Media Narrative
- Can prebiotics, probiotics or postbiotics help your ageing microbiome?
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