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Academic Publication Myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment and their targeting in cancer therapy
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Myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment and their targeting in cancer therapy
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Targeting of TAMs: can we be more clever than cancer cells?
АbstractWith increasing incidence and geography, cancer is one of the leading causes of death, reduced quality of life and disability worldwide. Principal progress in the development of new antican...
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer
Abstract Understanding the role of the tumor microenvironment (TME) in lung cancer is critical to improving patient outcomes. We identifi...
Regulatory mechanisms of PD-1/PD-L1 in cancers
AbstractImmune evasion contributes to cancer growth and progression. Cancer cells have the ability to activate different immune checkpoint pathways that harbor immunosuppressive functions. The prog...
Investigating the impact of combustible and electronic cigarettes on clonal hematopoiesis
Self-renewing hematopoietic stem cells (HSCs) produce billions of blood cells a day to maintain peripheral blood and immune cells in circulation. Inflammation can alter the balance of steady-state ...
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Associated Media Narrative
- Author Correction: Regulatory T cells in the mouse hypothalamus control immune activation and ameliorate metabolic impairments in high-calorie environments
- Exploring the relationship between vascular remodelling and tumour growth using agent-based modelling
- VesiclePy: A machine learning vesicle analysis toolbox for volume electron microscopy