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Academic Publication Glioblastoma multiforme: insights into pathogenesis, key signaling pathways, and therapeutic strategies
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Targeting of TAMs: can we be more clever than cancer cells?
АbstractWith increasing incidence and geography, cancer is one of the leading causes of death, reduced quality of life and disability worldwide. Principal progress in the development of new antican...
Vascular endothelial growth factor signaling in health and disease: from molecular mechanisms to therapeutic perspectives
Abstract Vascular endothelial growth factor (VEGF) signaling is a critical regulator of vasculogenesis, angiogenesis, and lymphangiogenesis, processes that are vital for the development o...
Glucagon-like peptide-1 receptor: mechanisms and advances in therapy
AbstractThe glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital component of the G protein-coupled receptor (GPCR) family and is found primarily on the surfaces of various cell ty...
Bioinformatics Analysis and Validation of Potential Markers Associated with Prediction and Prognosis of Gastric Cancer
Gastric cancer (GC) is one of the most common cancers worldwide. Most patients are diagnosed at the progressive stage of the disease, and current anticancer drug advancements are still lacking. The...
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer
Abstract Understanding the role of the tumor microenvironment (TME) in lung cancer is critical to improving patient outcomes. We identifi...
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