Academic Publication Drug-induced tolerant persisters in tumor: mechanism, vulnerability and perspective implication for clinical treatment
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Drug-induced tolerant persisters in tumor: mechanism, vulnerability and perspective implication for clinical treatment
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Drug tolerant persister cell plasticity in cancer: a revolutionary strategy for more effective anticancer therapies
AbstractNon-genetic mechanisms have recently emerged as important drivers of anticancer drug resistance. Among these, the drug tolerant persister (DTP) cell phenotype is attracting more and more at...
Emerging Therapeutic Strategies to Overcome Drug Resistance in Cancer Cells
The rise of drug resistance in cancer cells presents a formidable challenge in modern oncology, necessitating the exploration of innovative therapeutic strategies. This review investigates the late...
Immune evasion in cancer: mechanisms and cutting-edge therapeutic approaches
Abstract Immune evasion represents a significant challenge in oncology. It allows tumors to evade immune surveillance and destruction, thereby complicating therapeutic interventions and c...
Scientists shut down cancer DNA repair to overcome drug resistance
Cancer cells often survive treatment by fixing the DNA damage that therapy is meant to cause. Researchers found that UNI418 can disrupt this repair ability, leaving cancer cells more exposed. When ...
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Yes, highly correlated activity was mapped. An entry titled 'Scientists shut down cancer DNA repair to overcome drug resistance' discusses this: Cancer cells often survive treatment by fixing the DNA damage that therapy is meant to cause. Researchers found that UNI418 can disrupt this repair...
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