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Academic Publication Academic Publication

Molecular mechanisms of aging and anti-aging strategies

246
Citations
May 24, 2024
Published Date

Research Abstract & Technology Focus

AbstractAging is a complex and multifaceted process involving a variety of interrelated molecular mechanisms and cellular systems. Phenotypically, the biological aging process is accompanied by a gradual loss of cellular function and the systemic deterioration of multiple tissues, resulting in susceptibility to aging-related diseases. Emerging evidence suggests that aging is closely associated with telomere attrition, DNA damage, mitochondrial dysfunction, loss of nicotinamide adenine dinucleotide levels, impaired macro-autophagy, stem cell exhaustion, inflammation, loss of protein balance, deregulated nutrient sensing, altered intercellular communication, and dysbiosis. These age-related changes may be alleviated by intervention strategies, such as calorie restriction, improved sleep quality, enhanced physical activity, and targeted longevity genes. In this review, we summarise the key historical progress in the exploration of important causes of aging and anti-aging strategies in recent decades, which provides a basis for further understanding of the reversibility of aging phenotypes, the application prospect of synthetic biotechnology in anti-aging therapy is also prospected.
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What is the core focus of the research titled 'Molecular mechanisms of aging and anti-aging strategies'?

This literature focuses on: AbstractAging is a complex and multifaceted process involving a variety of interrelated molecular mechanisms and cellular systems. Phenotypically, the biological aging process is accompanied by a gradual loss of cellular function and the systemic ...

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What other academic literature is closely related to 'Molecular mechanisms of aging and anti-aging strategies'?

Yes, highly correlated activity was mapped. An entry titled 'Nonlinear dynamics of multi-omics profiles during human aging' discusses this: AbstractAging is a complex process associated with nearly all diseases. Understanding the molecular changes underlying aging and identifying therap...

Are there commercial applications of 'Molecular mechanisms of aging and anti-aging strategies' in market news publications?

Yes, highly correlated activity was mapped. An entry titled 'Scientists say NAD+ could slow aging and fight Alzheimer’s and Parkinson’s' discusses this: A global team of leading scientists is zeroing in on a tiny but powerful molecule that could reshape how we age. Known as NAD⁺, it plays a crucial ...

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