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Elucidating the specific mechanisms of the gut-brain axis: the short-chain fatty acids-microglia pathway

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May 21, 2025
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Elucidating the specific mechanisms of the gut-brain axis: the short-chain fatty acids-microglia pathway

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Short-Chain Fatty Acids and Human Health: From Metabolic Pathways to Current Therapeutic Implications

The gastrointestinal tract is home to trillions of diverse microorganisms collectively known as the gut microbiota, which play a pivotal role in breaking down undigested foods, such as dietary fibe...

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The Role of Short Chain Fatty Acids in Inflammation and Body Health

Short chain fatty acids (SCFAs), mainly including acetate, propionate and butyrate, are produced by intestinal bacteria during the fermentation of partially digested and indigestible polysaccharide...

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The gut commensal Blautia maintains colonic mucus function under low-fiber consumption through secretion of short-chain fatty acids

Abstract Beneficial gut bacteria are indispensable for developing colonic mucus and fully establishing its protective function against intestinal microorganis...

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Gut microbiome, short-chain fatty acids, alpha-synuclein, neuroinflammation, and ROS/RNS: Relevance to Parkinson's disease and therapeutic implications

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