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Recent Applications of PLGA in Drug Delivery Systems

203
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September 14, 2024
Published Date

Research Abstract & Technology Focus

Poly(lactic-co-glycolic acid) (PLGA) is a widely used biodegradable and biocompatible copolymer in drug delivery systems (DDSs). In this article, we highlight the critical physicochemical properties of PLGA, including its molecular weight, intrinsic viscosity, monomer ratio, blockiness, and end caps, that significantly influence drug release profiles and degradation times. This review also covers the extensive literature on the application of PLGA in delivering small-molecule drugs, proteins, peptides, antibiotics, and antiviral drugs. Furthermore, we discuss the role of PLGA-based DDSs in the treating various diseases, including cancer, neurological disorders, pain, and inflammation. The incorporation of drugs into PLGA nanoparticles and microspheres has been shown to enhance their therapeutic efficacy, reduce toxicity, and improve patient compliance. Overall, PLGA-based DDSs holds great promise for the advancement of the treatment and management of multiple chronic conditions.
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What is the core focus of the research titled 'Recent Applications of PLGA in Drug Delivery Systems'?

This literature focuses on: Poly(lactic-co-glycolic acid) (PLGA) is a widely used biodegradable and biocompatible copolymer in drug delivery systems (DDSs). In this article, we highlight the critical physicochemical properties of PLGA, including its molecular weight, intrins...

Are there open-source GitHub repositories related to Recent Applications of PLGA in Drug Delivery Systems?

Yes, open-source projects like future-agi/future-agi (Open-source, end-to-end platform for evaluating, observing, and improving LLM and AI agent applications. Tracing · Evals · Simulations · Datasets ·...) are actively building upon these concepts.

Which startups are commercializing the technology behind Recent Applications of PLGA in Drug Delivery Systems?

Products like Nitro by Rocketlane are bringing this to market. Their focus is: AI agents for modern service delivery.

What other academic literature is closely related to 'Recent Applications of PLGA in Drug Delivery Systems'?

Yes, highly correlated activity was mapped. An entry titled 'Recent Applications of PLGA in Drug Delivery Systems' discusses this: Poly(lactic-co-glycolic acid) (PLGA) is a widely used biodegradable and biocompatible copolymer in drug delivery systems (DDSs). In this article, w...

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